American Academy of Dermatology Says Give Beauty a Shot

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American Academy of Dermatology Says Give Beauty a Shot Posted by
American Academy of Dermatology Says Give Beauty a Shot: New Uses For

Botulinum Toxin

NEW YORK, Oct. 18 /PRNewswire/ -- Each year, more and more Americans are
turning to botulinum toxin to reverse the telltale signs of aging. Carefully
injected by dermatologists and dermatologic surgeons in very low doses,
botulinum toxin can dramatically soften frown lines, crows feet, and other
Speaking today at the American Academy of Dermatology's Derm Update 2000,
dermatologist Harold Brody, M.D., Clinical Professor of Dermatology, Emory
University School of Medicine, Atlanta, Georgia, discussed the recent advances
in botulinum toxin.
Botulinum toxin, best known as the cause of botulism food poisoning,
blocks nerve signals transmitted from the brain to the muscle, causing
paralysis of the injected muscle. It works locally by inhibiting the release
of acetylcholine, a neurotransmitter, from the nerve. Since botulinum toxin
decreases the patient's ability to frown or squint, it also safely and
effectively prevents the progressive worsening of these lines over time.
"Botulinum toxin has truly revolutionized the treatment of wrinkles," said
Dr. Brody. "What's even more exciting is that we continue to find new uses
for this toxin."
The most common uses of botulinum toxin that were developed by
dermatologists are the treatment of frown lines between the eyebrows
(glabella), crow's feet and forehead lines. In addition, dermatologists also
discovered that botulinum toxin can be used in the treatment neck band muscles
and malpositioned eyebrows.
Botulinum toxin has also been proven successful in treating individuals
who suffer from excessive sweating, or hyperhidrosis. Botulinum toxin can be
used to decrease sweating on the palms or soles, underarms, forehead or
genital areas by injecting the toxin into the affected areas. Once injected,
botulinum toxin paralyzes the sweat glands of the skin which are responsible
for excessive perspiration.
Recently, dermatologists have noted that both migraine and tension
headaches are improved when the forehead is treated with botulinum toxin. New
testing has demonstrated its effectiveness in the treatment of rashes due to
spasm of the anal or vaginal muscles, writer's cramp and spastic disorders,
such as post-stroke spasticity or neck muscle spasticity. Also significant is
its use before and after cosmetic dermatologic surgical resurfacing procedures
(lasers, peeling, dermabrasion) for sun-damaged skin to maintain good results.
When injected prior to the procedure, botulinum toxin allows smooth healing of
resurfacing by preventing movement. Injected after resurfacing, botulinum
toxin prevents the reappearance of movement-induced wrinkles.
Injecting botulinum toxin into the skin is a quick and easy in-office
procedure that takes less than 30 minutes. Within a week after a patient is
injected with botulinum toxin, the affected wrinkles will smooth out from
disuse of the muscle.
"Results typically last three-to-four months at the beginning of botulinum
toxin treatment, but as multiple sessions progress the time interval between
injections will increase due to both increased muscle thinning and conditioned
behavior modification on the part of the patient," explained Dr. Brody.
"Patients respond well to this treatment and are generally highly satisfied
with the results."
In 1989, the Food and Drug Administration approved botulinum toxin for
spasms of the eyelid and eye muscle problems. In 1991, it was discovered in
dermatology and ophthalmology that patients who were treated with botulinum
toxin also experienced the disappearance of wrinkles in the eye area. It is
presently an off-label use of an approved drug.
The American Academy of Dermatology, founded in 1938, is the largest, most
influential, and most representative of all dermatologic associations. With a
membership of over 13,000 dermatologists worldwide, the Academy is committed
to: advancing the science and art of medicine and surgery related to the skin;
advocating high standards in clinical practice, education, and research in
dermatology; supporting and enhancing patient care; and promoting a lifetime
of healthier skin, hair and nails. For more information, contact the AAD at
1-888-462-DERM or .
The American Society for Dermatologic Surgery (ASDS) was founded in 1970
to promote excellence in the field of dermatologic surgery and to foster the
highest standards of patient care. For more information on cosmetic skin
surgery and referrals to doctors in specific geographic areas, please contact
the ASDS Consumer Hotline, 1-800-441-ASDS (2737), during weekday business
hours or visit the Web site at .

SOURCE American Academy of Dermatology

-0- 10/18/2000

/CONTACT: Missy Gough, 847-240-1734, email,, or Karen

Klickmann, 847-240-1735, email,, or Jennifer Gale,

847-240-1730, email,, all of the American Academy of


Web Site: / /

Web Site: / /

CO: American Academy of Dermatology; American Society for Dermatologic


ST: New York




-- CGW009 --

4961 10/18/2000 12:03 EDT

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